LGR5 anticorps (AA 241-352)

N° du produit ABIN7158130

Cet anticorps anti-LGR5 est un anticorps Lapin Polyclonal détectant LGR5 dans IHC, ELISA et IF. Adapté pour Humain.

Aperçu rapide pour LGR5 anticorps (AA 241-352) (ABIN7158130)

Antigène: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGR5 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-LGR5 anticorps

Épitope: AA 241-352

Fonction: LGR5 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Leucine-rich repeat-containing G-protein coupled receptor 5 protein (241-352AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur LGR5

Antigène: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Autre désignation: LGR5

Sujet:

Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.

Aliases: FEX antibody, G protein coupled receptor 49 antibody, G protein coupled receptor 67 antibody, g protein-coupled receptor fex antibody, G-protein coupled receptor 49 antibody, G-protein coupled receptor 67 antibody, G-protein coupled receptor HG38 antibody, GPCR GPR49 antibody, GPR 49 antibody, GPR 67 antibody, GPR49 antibody, GPR67 antibody, GRP 49 antibody, GRP49 antibody, HG 38 antibody, HG38 antibody, Leucine rich repeat containing G protein coupled receptor 5 antibody, Leucine-rich repeat-containing G-protein coupled receptor 5 antibody, LGR 5 antibody, LGR5 antibody, LGR5_HUMAN antibody, MGC117008 antibody, Orphan G protein coupled receptor HG38 antibody

UniProt: O75473

Pathways: Signalisation WNT