KDM4A anticorps (AA 127-364) (FITC)
Aperçu rapide pour KDM4A anticorps (AA 127-364) (FITC) (ABIN7158697)
Antigène
Voir toutes KDM4A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 127-364
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Fonction
- KDM4A Antibody, FITC conjugated
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human Lysine-specific demethylase 4A protein (127-364AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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Autre désignation
- KDM4A
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Sujet
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Background: Histone demethylase that specifically demethylates \'Lys-9\' and \'Lys-36\' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 \'Lys-4\', H3 \'Lys-27\' nor H4 \'Lys-20\'. Demethylates trimethylated H3 \'Lys-9\' and H3 \'Lys-36\' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Aliases: JHDM3A antibody, JmjC domain containing histone demethylation protein 3A antibody, JmjC domain-containing histone demethylation protein 3A antibody, JMJD2 antibody, JMJD2A antibody, jumonji C domain containing histone demethylase 3A antibody, Jumonji domain containing 2 antibody, Jumonji domain containing 2A antibody, Jumonji domain containing protein 2A antibody, Jumonji domain-containing protein 2A antibody, KDM4A antibody, KDM4A_HUMAN antibody, KIAA0677 antibody, Lysine (K) specific demethylase 4A antibody, Lysine-specific demethylase 4A antibody, TDRD14A antibody, Tudor domain containing 14A antibody
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UniProt
- O75164
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Pathways
- L'effet Warburg
Antigène
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