MGMT anticorps (AA 4-207)

N° du produit ABIN7159622

Cet anticorps Lapin Polyclonal détecte spécifiquement MGMT dans IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour MGMT anticorps (AA 4-207) (ABIN7159622)

Antigène: MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MGMT est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-MGMT anticorps

Épitope: AA 4-207

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Methylated-DNA--protein-cysteine methyltransferase protein (4-207AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:10-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MGMT

Antigène: MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

Autre désignation: MGMT

Sujet:

Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Aliases: 6 O methylguanine DNA methyltransferase antibody, 6-O-methylguanine-DNA methyltransferase antibody, Agat antibody, AGT antibody, AI267024 antibody, EC 2.1.1.63 antibody, Methylated DNA protein cysteine methyltransferase antibody, Methylated-DNA--protein-cysteine methyltransferase antibody, Methylguanine DNA methyltransferase antibody, MGC107020 antibody, MGMT antibody, MGMT_HUMAN antibody, O 6 methylguanine DNA alkyltransferase antibody, O 6 methylguanine DNA methyltransferase antibody, O-6-methylguanine-DNA methyltransferase antibody, O-6-methylguanine-DNA-alkyltransferase antibody

UniProt: P16455

Pathways: Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus