MITF anticorps (AA 40-269)

N° du produit ABIN7159718

Cet anticorps Lapin Polyclonal détecte spécifiquement MITF dans IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour MITF anticorps (AA 40-269) (ABIN7159718)

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MITF est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-MITF anticorps

Épitope: AA 40-269

Fonction: MITF Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Microphthalmia-associated transcription factor protein (40-269aa)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MITF

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Autre désignation: MITF

Sujet:

Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to M-boxes (5'-TCATGTG-3') and symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

Aliases: Microphthalmia-associated transcription factor (Class E basic helix-loop-helix protein 32) (bHLHe32), MITF, BHLHE32

UniProt: O75030

Pathways: Chromatin Binding