MAPK7 anticorps (AA 1-310)

N° du produit ABIN7160008

Cet anticorps anti-MAPK7 est un anticorps Lapin Polyclonal détectant MAPK7 dans IHC, ELISA et IF. Adapté pour Humain.

Aperçu rapide pour MAPK7 anticorps (AA 1-310) (ABIN7160008)

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK7 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-MAPK7 anticorps

Épitope: AA 1-310

Fonction: MAPK7 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Mitogen-activated protein kinase 7 protein (1-310AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MAPK7

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Autre désignation: MAPK7

Sujet:

Background: Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression. Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction.

Aliases: Big MAP kinase 1 antibody, BMK 1 antibody, BMK 1 kinase antibody, BMK-1 antibody, BMK1 antibody, BMK1 Kinase antibody, EC 2.7.11.24 antibody, ERK 4 antibody, ERK 5 antibody, ERK-5 antibody, ERK4 antibody, ERK5 antibody, Extracellular signal regulated kinase 5 antibody, Extracellular signal-regulated kinase 5 antibody, MAP kinase 7 antibody, MAPK 7 antibody, MAPK7 antibody, Mitogen activated protein kinase 7 antibody, Mitogen-activated protein kinase 7 antibody, MK07_HUMAN antibody, OTTHUMP00000065906 antibody, OTTHUMP00000065907 antibody, PRKM 7 antibody, PRKM7 antibody, PROTEIN KINASE, MITOGEN-ACTIVATED, 7 antibody

UniProt: Q13164

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling