NLRP2 anticorps (AA 1-220)

N° du produit ABIN7160825

Cet anticorps Lapin Polyclonal détecte spécifiquement NLRP2 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour NLRP2 anticorps (AA 1-220) (ABIN7160825)

Antigène: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-NLRP2 anticorps

Épitope: AA 1-220

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human NACHT, LRR and PYD domains-containing protein 2 protein (1-220AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NLRP2

Antigène: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Autre désignation: NLRP2

Sujet:

Background: Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.

Aliases: CLR19.9 antibody, FLJ20510 antibody, Leucine rich repeat and PYD containing protein 2 antibody, LRR and PYD domains-containing protein 2 antibody, NACHT antibody, NACHT domain antibody, NACHT leucine rich repeat and PYD containing 2 antibody, NACHT LRR and PYD domains containing protein 2 antibody, NALP2 antibody, NALP2_HUMAN antibody, NBS1 antibody, NLR family pyrin domain containing 2 antibody, NLRP2 antibody, Nucleotide binding oligomerization domain leucine rich repeat and pyrin domain containing 2 antibody, Nucleotide-binding site protein 1 antibody, PAN1 antibody, PYPAF2 antibody, PYRIN containing APAF1 like protein2 antibody, PYRIN domain and NACHT domain-containing protein 1 antibody, PYRIN-containing APAF1-like protein 2 antibody

UniProt: Q9NX02

Pathways: Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome