NLRP2 anticorps (AA 1-220)

N° du produit ABIN7268939

Détail du produit anti-NLRP2 anticorps

Antigène: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Épitope: AA 1-220

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: NLRP2 Rabbit pAb

Séquence: MVSSAQMGFN LQALLEQLSQ DELSKFKYLI TTFSLAHELQ KIPHKEVDKA DGKQLVEILT THCDSYWVEM ASLQVFEKMH RMDLSERAKD EVREAALKSF NKRKPLSLGI TRKERPPLDV DEMLERFKTE AQAFTETKGN VICLGKEVFK GKKPDKDNRC RYILKTKFRE MWKSWPGDSK EVQVMAERYK MLIPFSNPRV LPGPFSYTVV LYGPAGLGKT

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NLRP2 (NP_060322.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NLRP2

Antigène: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Autre désignation: NLRP2 (NLRP2 Produits)

Synonymes: anticorps CLR19.9, anticorps NALP2, anticorps NBS1, anticorps PAN1, anticorps PYPAF2, anticorps NLRP2, anticorps E330007A02Rik, anticorps Nalp2, anticorps NLR family pyrin domain containing 2, anticorps NACHT, LRR and PYD domains-containing protein 2, anticorps NLR family pyrin domain containing 7, anticorps NLR family, pyrin domain containing 2, anticorps NLRP2, anticorps LOC100301026, anticorps LOC100387349, anticorps NLRP7, anticorps Nlrp2

Sujet: This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms.,NLRP2,CLR19.9,NALP2,NBS1,PAN1,PYPAF2,Cell Biology & Developmental Biology,Apoptosis,Caspases,NLRP2

Poids moléculaire: 96kDa/117kDa/118kDa/120kDa

ID gène: 55655

UniProt: Q9NX02

Pathways: Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome