NADPH Oxidase 4 anticorps (AA 210-424)

N° du produit ABIN7161010

Cet anticorps anti-NADPH Oxidase 4 est un anticorps Lapin Polyclonal détectant NADPH Oxidase 4 dans ELISA, IHC et IF. Adapté pour Humain.

Aperçu rapide pour NADPH Oxidase 4 anticorps (AA 210-424) (ABIN7161010)

Antigène: NADPH Oxidase 4 (NOX4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NADPH Oxidase 4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-NADPH Oxidase 4 anticorps

Épitope: AA 210-424

Fonction: NOX4 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human NADPH oxidase 4 protein (210-424AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NADPH Oxidase 4

Antigène: NADPH Oxidase 4 (NOX4)

Autre désignation: NOX4

Sujet:

Background: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity.

Aliases: Kidney oxidase 1 antibody, Kidney oxidase-1 antibody, Kidney superoxide producing NADPH oxidase antibody, Kidney superoxide-producing NADPH oxidase antibody, KOX 1 antibody, KOX antibody, Kox-1 antibody, KOX1 antibody, NADPH antibody, NADPH oxidase 4 antibody, Nox4 antibody, NOX4_HUMAN antibody, Renal NAD(P)H oxidase antibody, Renal NAD(P)H-oxidase antibody, RENOX antibody

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration