LCAT anticorps (AA 25-433) (HRP)

N° du produit ABIN7163130

L’anticorps Lapin Polyclonal anti-LCAT a été validé pour ELISA. Il convient pour détecter LCAT dans des échantillons de Humain.

Aperçu rapide pour LCAT anticorps (AA 25-433) (HRP) (ABIN7163130)

Antigène: LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LCAT est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-LCAT anticorps (HRP)

Épitope: AA 25-433

Fonction: LCAT Antibody, HRP conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Phosphatidylcholine-sterol acyltransferase protein (25-433AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur LCAT

Antigène: LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

Autre désignation: LCAT

Sujet:

Background: Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms.

Aliases: LCAT antibody, LCAT_HUMAN antibody, Lecithin cholesterol acyltransferase antibody, Lecithin-cholesterol acyltransferase antibody, Phosphatidylcholine sterol acyltransferase antibody, Phosphatidylcholine-sterol acyltransferase antibody, Phospholipid cholesterol acyltransferase antibody, Phospholipid-cholesterol acyltransferase antibody

UniProt: P04180

Pathways: Lipid Metabolism