Lamin A/C anticorps (AA 385-572)

N° du produit ABIN7164247

Détail du produit anti-Lamin A/C anticorps

Antigène: Lamin A/C (LMNA)

Épitope: AA 385-572

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin A/C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain, Rat

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Prelamin-A/C protein (385-572AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Lamin A/C

Antigène: Lamin A/C (LMNA)

Autre désignation: LMNA (LMNA Produits)

Synonymes: anticorps CDCD1, anticorps CDDC, anticorps CMD1A, anticorps CMT2B1, anticorps EMD2, anticorps FPL, anticorps FPLD, anticorps FPLD2, anticorps HGPS, anticorps IDC, anticorps LDP1, anticorps LFP, anticorps LGMD1B, anticorps LMN1, anticorps LMNC, anticorps LMNL1, anticorps PRO1, anticorps Dhe, anticorps 2459, anticorps 74/76, anticorps CG6944, anticorps D5, anticorps DM[[O]], anticorps Dm, anticorps Dm(0), anticorps Dm0, anticorps Dm1, anticorps Dm2, anticorps DmLamin, anticorps DmO, anticorps Dm[[0]], anticorps Dm[[1]], anticorps Dm[[2]], anticorps Dm[[mit]], anticorps Dm[[o]], anticorps Dmel\\CG6944, anticorps Dmo, anticorps LAM, anticorps Lam Dm[[0]], anticorps Lam(Dm0), anticorps LamDm[[0]], anticorps LamDm[[o]], anticorps Lam[[Dm0]], anticorps Lamin Dm[[0]], anticorps jf27, anticorps l(2)04643, anticorps l(2)25Ec, anticorps l(2)gdh-7, anticorps l(2)gdh7, anticorps l(2)jf27, anticorps lam, anticorps lamDm0, anticorps lamDm[[0]], anticorps lamin, anticorps lamin Dm0, anticorps lamin Dm[[0]], anticorps misg, anticorps nlam, anticorps cb948, anticorps fk66d12, anticorps wu:fk66d12, anticorps lmna-A, anticorps fpl, anticorps idc, anticorps lfp, anticorps cddc, anticorps emd2, anticorps fpld, anticorps hgps, anticorps ldp1, anticorps lmn1, anticorps lmnc, anticorps pro1, anticorps cdcd1, anticorps cmd1a, anticorps cmt2b1, anticorps lgmd1b, anticorps Lamin-A, anticorps lamin-L(III)-like, anticorps lamin A/C, anticorps lamin A, anticorps Lamin, anticorps lamin A/C L homeolog, anticorps lamin-L(III)-like, anticorps LMNA, anticorps Lmna, anticorps Lam, anticorps lmna, anticorps lmna.L, anticorps LMINA

Sujet:

Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone.

Aliases: 70 kDa lamin antibody, Cardiomyopathy dilated 1A (autosomal dominant) antibody, CDCD1 antibody, CDDC antibody, CMD1A antibody, CMT2B1 antibody, EMD2 antibody, FPL antibody, FPLD antibody, FPLD2 antibody, HGPS antibody, IDC antibody, Lamin A antibody, Lamin A/C antibody, Lamin A/C like 1 antibody, Lamin antibody, Lamin C antibody, lamin-a antibody, Lamin-A/C antibody, LDP1 antibody, LFP antibody, LGMD1B antibody, Limb girdle muscular dystrophy 1B (autosomal dominant) antibody, LMN 1 antibody, LMN A antibody, LMN C antibody, LMN1 antibody, LMNA antibody, LMNA_HUMAN antibody, LMNC antibody, LMNL1 antibody, Prelamin A/C antibody, PRO1 antibody, Renal carcinoma antigen NY REN 32 antibody, Renal carcinoma antigen NY-REN-32 antibody, Renal carcinoma antigen NYREN32 antibody

UniProt: P02545

Pathways: Apoptose, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus