PITRM1 anticorps (AA 758-1037)
Aperçu rapide pour PITRM1 anticorps (AA 758-1037) (ABIN7164274)
Antigène
Voir toutes PITRM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 758-1037
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Réactivité croisée
- Humain, Souris
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Purification
- Antigen Affinity Purified
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Immunogène
- Recombinant Human Presequence protease, mitochondrial protein (758-1037AA)
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Isotype
- IgG
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Indications d'application
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))
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Autre désignation
- PITRM1
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Sujet
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Background: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.
Aliases: hMP1 antibody, hPreP antibody, KIAA1104 antibody, Metalloprotease 1 antibody, MGC138192 antibody, MGC141929 antibody, mitochondrial antibody, MP1 antibody, Pitrilysin metallopeptidase 1 antibody, Pitrilysin metalloproteinase 1 antibody, PITRM 1 antibody, PITRM1 antibody, PreP antibody, PreP peptidasome antibody, PREP_HUMAN antibody, Presequence protease antibody, Presequence protease mitochondrial antibody
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UniProt
- Q5JRX3
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Pathways
- Signalisation PI3K-Akt, SARS-CoV-2 Protein Interactome
Antigène
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