CYR61 anticorps (AA 25-381)

N° du produit ABIN7165238

Cet anticorps Lapin Polyclonal détecte spécifiquement CYR61 dans IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour CYR61 anticorps (AA 25-381) (ABIN7165238)

Antigène: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYR61 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-CYR61 anticorps

Épitope: AA 25-381

Fonction: CYR61 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Protein CYR61 protein (25-381AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CYR61

Antigène: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Autre désignation: CYR61

Sujet:

Background: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.

Aliases: 3CH61 antibody, CCN 1 antibody, CCN family member 1 antibody, CCN1 antibody, CYR 61 antibody, Cyr61 antibody, CYR61 protein antibody, CYR61_HUMAN antibody, Cysteine rich angiogenic inducer 61 antibody, Cysteine rich heparin binding protein 61 antibody, Cysteine-rich angiogenic inducer 61 antibody, GIG 1 antibody, GIG1 antibody, IBP-10 antibody, IGF-binding protein 10 antibody, Igfbp 10 antibody, IGFBP-10 antibody, Igfbp10 antibody, Insulin like growth factor binding protein 10 antibody, Insulin-like growth factor-binding protein 10 antibody, Protein CYR61 antibody, Protein GIG1 antibody

UniProt: O00622

Pathways: Positive Regulation of Endopeptidase Activity, Growth Factor Binding