Patched 1 anticorps (AA 1180-1411)

N° du produit ABIN7165903

Détail du produit anti-Patched 1 anticorps

Antigène: Patched 1 (PTCH1)

Épitope: AA 1180-1411

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Patched 1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Protein patched homolog 1 protein (1180-1411AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Patched 1

Antigène: Patched 1 (PTCH1)

Autre désignation: PTCH1 (PTCH1 Produits)

Synonymes: anticorps BCNS, anticorps HPE7, anticorps NBCCS, anticorps PTC, anticorps PTC1, anticorps PTCH, anticorps PTCH11, anticorps lep, anticorps ptc1, anticorps ptc2, anticorps Ptch, anticorps Ptch2, anticorps Ptc-1, anticorps XPtc1, anticorps patched, anticorps patched1, anticorps A230106A15Rik, anticorps Ptc, anticorps Ptc1, anticorps mes, anticorps patched 1, anticorps patched 1 L homeolog, anticorps Protein patched homolog 1, anticorps PTCH1, anticorps ptch1, anticorps Ptch1, anticorps ptch1.L, anticorps ptc-1

Sujet:

Background: Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog\'s proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.

Aliases: A230106A15Rik antibody, BCNS antibody, FLJ26746 antibody, FLJ42602 antibody, Holoprosencephaly 7 antibody, HPE7 antibody, mes antibody, NBCCS antibody, OTTHUMP00000021709 antibody, OTTHUMP00000021710 antibody, Patched antibody, Patched (Drosophila) homolog antibody, Patched 1 antibody, Patched homolog (Drosophila) antibody, Patched homolog 1 (Drosophila) antibody, Patched homolog 1 antibody, Patched protein homolog 1 antibody, Protein patched homolog 1 antibody, PTC antibody, PTC1 antibody, PTC1_HUMAN antibody, PTCH antibody, PTCH protein +12b antibody, PTCH protein +4' antibody, PTCH protein -10 antibody, PTCH protein antibody, ptch1 antibody, PTCH1 protein antibody, PTCH11 antibody, Ptch2 antibody

UniProt: Q13635

Pathways: Signalisation Hedgehog, Carbohydrate Homeostasis, Tube Formation