SNCA anticorps (pSer129)

N° du produit ABIN712391

L’anticorps anti-SNCA Polyclonal Lapin est utilisé pour la détection de SNCA dans des échantillons de Humain. Il a été validé pour WB, IHC (p), FACS, IF (cc), IF (p) et IHC (fro).

Aperçu rapide pour SNCA anticorps (pSer129) (ABIN712391)

Antigène: SNCA (Synuclein, alpha (SNCA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNCA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-SNCA anticorps

Épitope: pSer129

Fonction: phospho-Alpha synuclein (Ser129) Polyclonal Antibody

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human SNCA around the phosphorylation site of Ser129 [MP(p-S)EE]

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000),

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SNCA

Antigène: SNCA (Synuclein, alpha (SNCA))

Autre désignation: Alpha synuclein

Sujet:

Synonyms: SNCAphospho S129, alpha Synuclein phospho S129 ,alpha-Synuclein Ser129, Synuclein alphaSer129, Alpha synuclein, Alpha-Synuclein, Alpha-synuclein, isoform NACP140, alpha SYN, MGC105443, MGC110988, MGC127560, MGC64356, NACP, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid , precursor of, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, PARK 1, PARK 4, PARK1, PARK4, Parkinson disease autosomal dominant, Lewy body 4, Parkinson disease familial 1, PD 1, PD1, Syn, SNCA, Snca synuclein, alpha non A4 component of amyloid precursor, SYUA_HUMAN, Synuclein alpha, Synuclein, alpha non A4 component of amyloid precursor,

Background: The synucleins, including Alpha-synuclein (also designated NACP for nonamyloid component precursor),Beta-synuclein (also designated PNP 14 for neuroprotein 14)and Gamma-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1)are presynaptic protein abundant in neurons. Alpha-synuclein, a component of Alzheimer?s disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of Alpha-synucleinand Beta-synuclein may be important during hematopoetic cell differentiation. In patients with Parkinson?s disease, a mutant form of Alpha-synuclein has been found and Gamma-synuclein is associated with axonal pathology.

ID gène: 6622

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity