MCF2 anticorps (AA 705-925)
Aperçu rapide pour MCF2 anticorps (AA 705-925) (ABIN7166480)
Antigène
Voir toutes MCF2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 705-925
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Réactivité croisée
- Humain
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Purification
- Antigen Affinity Purified
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Immunogène
- Recombinant Human Proto-oncogene DBL protein (705-925AA)
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Isotype
- IgG
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Indications d'application
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))
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Autre désignation
- MCF2
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Sujet
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Background: Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.
Aliases: MCF2 antibody, DBLProto-oncogene DBL antibody, Proto-oncogene MCF-2) [Cleaved into: MCF2-transforming protein, DBL-transforming protein] antibody
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UniProt
- P10911
Antigène
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