RASSF5 anticorps (AA 1-265)
Aperçu rapide pour RASSF5 anticorps (AA 1-265) (ABIN7167138)
Antigène
Voir toutes RASSF5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-265
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Fonction
- RASSF5 Antibody
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Purification
- Antigen Affinity Purified
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Immunogène
- Recombinant Human Ras association domain-containing protein 5 protein (1-265AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))
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Autre désignation
- RASSF5
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Sujet
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Background: Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.
Aliases: Maxp 1 antibody, MAXP1 antibody, MGC10823 antibody, MGC17344 antibody, New ras effector 1 antibody, NORE 1 antibody, NORE1 antibody, NORE1A antibody, NORE1B antibody, Novel Ras effector 1 antibody, RAP1 Binding Protein antibody, RAPL antibody, Ras association (RalGDS/AF 6) domain family 5 antibody, Ras association (RalGDS/AF 6) domain family member 5 antibody, Ras association domain containing family protein 5 antibody, Ras association domain-containing protein 5 antibody, Ras effector like protein antibody, RASF5_HUMAN antibody, RASSF 3 antibody, RASSF 5 antibody, RASSF3 antibody, RASSF5 antibody, Regulator for cell adhesion and polarization enriched in lymphoid tissue antibody, Regulator for cell adhesion and polarization enriched in lymphoid tissues antibody, Tumor suppressor RASSF3 antibody
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UniProt
- Q8WWW0
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Pathways
- TCR Signaling
Antigène
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