Septin 2 anticorps (AA 1-361)

N° du produit ABIN7168865

Cet anticorps Lapin Polyclonal détecte spécifiquement Septin 2 dans ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour Septin 2 anticorps (AA 1-361) (ABIN7168865)

Antigène: Septin 2 (SEPT2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Septin 2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Septin 2 anticorps

Épitope: AA 1-361

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Septin-2 protein (1-361AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Septin 2

Antigène: Septin 2 (SEPT2)

Autre désignation: SEPT2

Sujet:

Background: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

Aliases: SEPTIN2 antibody, DIFF6 antibody, KIAA0158 antibody, NEDD5 antibody, SEPT2 antibody, Septin-2 antibody, Neural precursor cell expressed developmentally down-regulated protein 5 antibody, NEDD-5 antibody

UniProt: Q15019