MARK1 anticorps (AA 560-700)

N° du produit ABIN7169067

L’anticorps Lapin Polyclonal anti-MARK1 a été validé pour WB, ELISA et IHC. Il convient pour détecter MARK1 dans des échantillons de Humain.

Aperçu rapide pour MARK1 anticorps (AA 560-700) (ABIN7169067)

Antigène: MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-MARK1 anticorps

Épitope: AA 560-700

Fonction: MARK1 Antibody

Réactivité croisée: Rat

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Serine/threonine-protein kinase MARK1 protein (560-700AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MARK1

Antigène: MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))

Autre désignation: MARK1

Sujet:

Background: Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).

Aliases: KIAA1477 antibody, MAP/microtubule affinity regulating kinase 1 antibody, MAP/microtubule affinity-regulating kinase 1 antibody, MARK 1 antibody, MARK antibody, Mark1 antibody, MARK1_HUMAN antibody, MGC126512 antibody, MGC126513 antibody, Serine/threonine protein kinase MARK1 antibody, Serine/threonine-protein kinase MARK1 antibody

UniProt: Q9P0L2

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2