PAK3 anticorps (AA 70-190) (Biotin)

N° du produit ABIN7169129

Cet anticorps Lapin Polyclonal détecte spécifiquement PAK3 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour PAK3 anticorps (AA 70-190) (Biotin) (ABIN7169129)

Antigène: PAK3

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK3 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-PAK3 anticorps (Biotin)

Épitope: AA 70-190

Fonction: PAK3 Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Serine/threonine-protein kinase PAK 3 protein (70-190AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PAK3

Antigène: PAK3

Autre désignation: PAK3

Sujet:

Background: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development.

Aliases: PAK3 antibody, OPHN3 antibody, Serine/threonine-protein kinase PAK 3 antibody, EC 2.7.11.1 antibody, Beta-PAK antibody, Oligophrenin-3 antibody, p21-activated kinase 3 antibody, PAK-3 antibody

UniProt: O75914