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SMUG1 anticorps (AA 1-177) (Biotin)

SMUG1 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7169741
  • Antigène Voir toutes SMUG1 Anticorps
    SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))
    Épitope
    • 9
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-177
    Reactivité
    • 45
    • 18
    • 17
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 39
    • 5
    • 1
    Lapin
    Clonalité
    • 43
    • 2
    Polyclonal
    Conjugué
    • 25
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SMUG1 est conjugé à/à la Biotin
    Application
    • 32
    • 23
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Single-strand selective monofunctional uracil DNA glycosylase protein (1-177AA)
    Isotype
    IgG
    Top Product
    Discover our top product SMUG1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))
    Autre désignation
    SMUG1 (SMUG1 Produits)
    Synonymes
    anticorps SMUG1, anticorps xsmug1, anticorps 1200013B09Rik, anticorps A930006H09Rik, anticorps C85220, anticorps FDG, anticorps HMUDG, anticorps UNG3, anticorps single-strand-selective monofunctional uracil-DNA glycosylase 1, anticorps single-strand selective monofunctional uracil DNA glycosylase, anticorps single-strand-selective monofunctional uracil-DNA glycosylase 1 L homeolog, anticorps SMUG1, anticorps smug1, anticorps smuG1, anticorps smuG, anticorps LOC5577584, anticorps CpipJ_CPIJ002767, anticorps Smug1, anticorps smug1.L
    Sujet

    Background: Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.

    Aliases: FDG antibody, HMUDG antibody, MGC104370 antibody, Single strand selective monofunctional uracil DNA glycosylase 1 antibody, Single strand selective monofunctional uracil DNA glycosylase antibody, Single-strand selective monofunctional uracil DNA glycosylase antibody, SMUG 1 antibody, Smug1 antibody, SMUG1 protein antibody, SMUG1_HUMAN antibody, UNG 3 antibody, UNG3 antibody

    UniProt
    Q53HV7
    Pathways
    Réparation de l'ADN
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