Sonic Hedgehog anticorps (AA 51-300)
Aperçu rapide pour Sonic Hedgehog anticorps (AA 51-300) (ABIN7170326)
Antigène
Voir toutes Sonic Hedgehog (SHH) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 51-300
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Fonction
- SHH Antibody
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human Sonic hedgehog protein (51-300AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Sonic Hedgehog (SHH)
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Autre désignation
- SHH
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Sujet
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Background: Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).
Aliases: HHG 1 antibody, HHG-1 antibody, HHG1 antibody, HLP 3 antibody, HLP3 antibody, Holoprosencephaly 3 antibody, HPE 3 antibody, HPE3 antibody, MCOPCB5 antibody, shh antibody, SHH_HUMAN antibody, SMMC I antibody, SMMCI antibody, Sonic Hedgehog (Drosophila) homolog antibody, sonic hedgehog homolog (Drosophila) antibody, Sonic hedgehog homolog antibody, Sonic hedgehog protein antibody, Sonic hedgehog protein C-product antibody, TPT antibody, TPTPS antibody
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UniProt
- Q15465
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Pathways
- Signalisation Hedgehog, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Antigène
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