Sortilin 1 anticorps (AA 328-457) (FITC)

N° du produit ABIN7170337

Cet anticorps anti-Sortilin 1 est un anticorps Lapin Polyclonal détectant Sortilin 1 dans . Adapté pour Humain.

Aperçu rapide pour Sortilin 1 anticorps (AA 328-457) (FITC) (ABIN7170337)

Antigène: Sortilin 1 (SORT1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sortilin 1 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-Sortilin 1 anticorps (FITC)

Épitope: AA 328-457

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Sortilin protein (328-457AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Sortilin 1

Antigène: Sortilin 1 (SORT1)

Autre désignation: SORT1

Sujet:

Background: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.

Aliases: 100 kDa NT receptor antibody, Glycoprotein 95 antibody, Gp 95 antibody, Gp95 antibody, LDLCQ6 antibody, Neurotensin receptor 3 antibody, NT 3 antibody, NT3 antibody, NTR 3 antibody, NTR3 antibody, OTTHUMP00000013784 antibody, SORT 1 antibody, SORT_HUMAN antibody, SORT1 (gene name) antibody, Sort1 antibody, Sortilin 1 antibody, Sortilin antibody

UniProt: Q99523

Pathways: Neurotrophin Signaling Pathway