Tuberin anticorps (AA 1396-1496)

N° du produit ABIN7173643

Cet anticorps anti-Tuberin est un anticorps Lapin Polyclonal détectant Tuberin dans ELISA, WB et IF. Adapté pour Humain.

Aperçu rapide pour Tuberin anticorps (AA 1396-1496) (ABIN7173643)

Antigène: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tuberin est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Tuberin anticorps

Épitope: AA 1396-1496

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Tuberin protein (1396-1496AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Tuberin

Antigène: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Autre désignation: TSC2

Sujet:

Background: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5.

Aliases: FLJ43106 antibody, LAM antibody, OTTHUMP00000158940 antibody, OTTHUMP00000198394 antibody, OTTHUMP00000198395 antibody, PPP1R160 antibody, Protein phosphatase 1, regulatory subunit 160 antibody, TSC complex subunit 2 antibody, tsc2 antibody, TSC2_HUMAN antibody, TSC4 antibody, TSC4 gene, formerly antibody, TSC4, formerly antibody, Tuberin antibody, Tuberous sclerosis 2 antibody, Tuberous sclerosis 2 protein antibody, Tuberous sclerosis 2 protein homolog antibody

UniProt: P49815

Pathways: Signalisation RTK, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus