DcR2 anticorps (AA 257-386)

N° du produit ABIN7173837

L’anticorps anti-DcR2 Polyclonal Lapin est utilisé pour la détection de DcR2 dans des échantillons de Humain. Il a été validé pour ELISA et IHC.

Aperçu rapide pour DcR2 anticorps (AA 257-386) (ABIN7173837)

Antigène: DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DcR2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-DcR2 anticorps

Épitope: AA 257-386

Fonction: TNFRSF10D Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Tumor necrosis factor receptor superfamily member 10D protein (257-386AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DcR2

Antigène: DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))

Autre désignation: TNFRSF10D

Sujet:

Background: Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.

Aliases: CD 264 antibody, CD264 antibody, DcR 2 antibody, DcR2 antibody, Decoy receptor 2 antibody, Decoy with truncated death domain antibody, OTTHUMP00000123528 antibody, TNF receptor related receptor for TRAIL antibody, TNF related apoptosis inducing ligand receptor 4 antibody, TNF-related apoptosis-inducing ligand receptor 4 antibody, TNFRSF 10D antibody, TNFRSF10D antibody, TR10D_HUMAN antibody, TRAIL R4 antibody, TRAIL receptor 4 antibody, TRAIL receptor with a truncated death domain antibody, TRAIL-R4 antibody, TRAILR4 antibody, TRUNDD antibody, Tumor necrosis factor receptor superfamily member 10D antibody, Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain antibody

UniProt: Q9UBN6

Pathways: Apoptose