TWIST1 anticorps (AA 1-80)

N° du produit ABIN7173945

L’anticorps Lapin Polyclonal anti-TWIST1 a été validé pour WB et ELISA. Il convient pour détecter TWIST1 dans des échantillons de Humain.

Aperçu rapide pour TWIST1 anticorps (AA 1-80) (ABIN7173945)

Antigène: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TWIST1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TWIST1 anticorps

Épitope: AA 1-80

Fonction: TWIST1 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Twist-related protein 1 protein (1-80AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TWIST1

Antigène: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Autre désignation: TWIST1

Sujet:

Background: Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity).

Aliases: ACS3 antibody, B-HLH DNA binding protein antibody, bHLHa38 antibody, BPES2 antibody, BPES3 antibody, Class A basic helix-loop-helix protein 38 antibody, CRS antibody, CRS1 antibody, CSO antibody, H-twist antibody, OTTHUMP00000116043 antibody, SCS antibody, Twist basic helix loop helix transcription factor 1 antibody, Twist family bHLH transcription factor 1 antibody, Twist homolog 1 (Drosophila) antibody, Twist homolog 1 antibody, TWIST homolog of drosophila antibody, Twist related protein 1 antibody, Twist-related protein 1 antibody, TWIST1 antibody, TWST1_HUMAN antibody

UniProt: Q15672

Pathways: Signalisation p53, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity