ROR2 anticorps (AA 752-926)

N° du produit ABIN7174072

Détail du produit anti-ROR2 anticorps

Antigène: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Épitope: AA 752-926

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ROR2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Tyrosine-protein kinase transmembrane receptor ROR2 protein (752-926AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ROR2

Antigène: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Autre désignation: ROR2 (ROR2 Produits)

Synonymes: anticorps BDB, anticorps BDB1, anticorps NTRKR2, anticorps Ntrkr2, anticorps mRor2, anticorps ROR2, anticorps bdb, anticorps bdb1, anticorps Xror2, anticorps ntrkr2, anticorps MGC97773, anticorps LOC100219935, anticorps ror2, anticorps xror2, anticorps receptor tyrosine kinase like orphan receptor 2, anticorps receptor tyrosine kinase-like orphan receptor 2, anticorps receptor tyrosine kinase like orphan receptor 2 L homeolog, anticorps ROR2, anticorps Ror2, anticorps ror2, anticorps ror2.L

Sujet:

Background: Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).

Aliases: BDB antibody, BDB1 antibody, Brachydactyly type B antibody, EC 2.7.10.1 antibody, MGC163394 antibody, Neurotrophic tyrosine kinase antibody, Neurotrophic tyrosine kinase, receptor related 2 antibody, NTRKR2 antibody, Receptor tyrosine kinase-like orphan receptor 2 antibody, receptor-related 2 antibody, ROR2 antibody, ROR2_HUMAN antibody, Tyrosine protein kinase transmembrane receptor ROR2 antibody, Tyrosine-protein kinase transmembrane receptor Ror2 antibody

UniProt: Q01974

Pathways: Signalisation RTK, Signalisation WNT