RELB anticorps (pSer551)
Aperçu rapide pour RELB anticorps (pSer551) (ABIN713396)
Antigène
Voir toutes RELB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer551
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Homologie
- Human,Mouse,Rat,Cow,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic phosphopeptide derived from human RelB around the phosphorylation site of Ser551
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))
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Autre désignation
- RelB
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Sujet
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Synonyms: RELB phospho S551, RelB phospho Ser551, RelB Ser551, I REL, IREL, Nuclear factor of kappa light polypeptide gene enhancer in B cells 3, RelB, Reticuloendotheliosis viral oncogene homolog B, Transcription factor RelB, v rel avian reticuloendotheliosis viral oncogene homolog, v rel reticuloendotheliosis viral oncogene homolog B, RELB_HUMAN, I-Rel.
Background: The NFKB complex consists of NFKB1 or NFKB2 bound to REL, RELA, or RELB. The NFKB complex is inhibited by I kappa B proteins (NFKBIA, or NFKBIB), which inactivate NF kappa B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I kappa B proteins by kinases (IKBKA, or IKBKB,) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B complex.
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ID gène
- 5971
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Pathways
- Signalisation NF-kappaB, Signalisation RTK
Antigène
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