PDK3 anticorps (AA 131-362)

N° du produit ABIN7176880

Cet anticorps anti-PDK3 est un anticorps Lapin Polyclonal détectant PDK3 dans WB et ELISA. Adapté pour Souris.

Aperçu rapide pour PDK3 anticorps (AA 131-362) (ABIN7176880)

Antigène: PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDK3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PDK3 anticorps

Épitope: AA 131-362

Réactivité croisée: Humain, Souris, Rat

Purification: >95%, Protein G purified

Immunogène: Recombinant Mouse [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial protein (131-362AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PDK3

Antigène: PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

Autre désignation: Pdk3

Sujet:

Background: Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species (By similarity).

Aliases: Pdk3 antibody, [Pyruvate dehydrogenase antibody, acetyl-transferring)] kinase isozyme 3 antibody, mitochondrial antibody, EC 2.7.11.2 antibody, Pyruvate dehydrogenase kinase isoform 3 antibody

UniProt: Q922H2

Pathways: Signalisation PI3K-Akt, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg