Angiopoietin 2 anticorps (AA 19-483)

N° du produit ABIN7176944

Cet anticorps Lapin Polyclonal détecte spécifiquement Angiopoietin 2 dans WB, IHC et ELISA. Il présente une réactivité envers Souris.

Aperçu rapide pour Angiopoietin 2 anticorps (AA 19-483) (ABIN7176944)

Antigène: Angiopoietin 2 (ANGPT2)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Angiopoietin 2 anticorps

Épitope: AA 19-483

Fonction: Angpt2 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Mouse Angiopoietin-2 protein (19-483AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Angiopoietin 2

Antigène: Angiopoietin 2 (ANGPT2)

Autre désignation: Angpt2

Sujet:

Background: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal

Aliases: Angpt2 antibody, Agpt2Angiopoietin-2 antibody, ANG-2 antibody

UniProt: O35608

Pathways: Signalisation RTK