Survivin anticorps (AA 1-140)

N° du produit ABIN7176985

Cet anticorps anti-Survivin est un anticorps Lapin Polyclonal détectant Survivin dans WB et ELISA. Adapté pour Souris.

Aperçu rapide pour Survivin anticorps (AA 1-140) (ABIN7176985)

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Survivin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Survivin anticorps

Épitope: AA 1-140

Fonction: Birc5 Antibody

Réactivité croisée: Humain

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Mouse Baculoviral IAP repeat-containing protein 5 protein (1-140AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Survivin

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Autre désignation: Birc5

Sujet:

Background: Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex, directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7.

Aliases: Birc5 antibody, Api4 antibody, Iap4Baculoviral IAP repeat-containing protein 5 antibody, Apoptosis inhibitor 4 antibody, Apoptosis inhibitor survivin antibody, TIAP antibody

UniProt: O70201

Pathways: Apoptose, Cycle Cellulaire, Nuclear Hormone Receptor Binding