Sonic Hedgehog anticorps (AA 24-197) (HRP)
Aperçu rapide pour Sonic Hedgehog anticorps (AA 24-197) (HRP) (ABIN7179869)
Antigène
Voir toutes Sonic Hedgehog (SHH) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 24-197
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Fonction
- shha Antibody, HRP conjugated
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Réactivité croisée
- Poisson zèbre (Danio rerio)
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Zebrafish Sonic hedgehog protein A protein (24-197AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Sonic Hedgehog (SHH)
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Autre désignation
- shha
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Sujet
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Background: Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes. Displays floor plate-inducing activity. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity).
Aliases: shha antibody, shh antibody, vhh1 antibody, Sonic hedgehog protein A antibody, SHHA antibody, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains antibody, ShhNC antibody, VHH-1) [Cleaved into: Sonic hedgehog protein A N-product antibody, Shh N-terminal processed signaling domains antibody, ShhNp antibody, Sonic hedgehog protein N-product antibody, ShhN)] antibody
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UniProt
- Q92008
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Pathways
- Signalisation Hedgehog, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Antigène
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