CTNND1 anticorps (Tyr228)

N° du produit ABIN7179986

Cet anticorps Lapin Polyclonal détecte spécifiquement CTNND1 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour CTNND1 anticorps (Tyr228) (ABIN7179986)

Antigène: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTNND1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-CTNND1 anticorps

Épitope: Tyr228

Fonction: CTNND1 (Ab-228) Antibody

Réactivité croisée: Souris, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized non-phosphopeptide derived from Human Catenin-delta1 around the phosphorylation site of tyrosine 228 (D-N-Y(p)-G-S).

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CTNND1

Antigène: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Autre désignation: CTNND1

Sujet:

Background: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway By similarity. Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.Keirsebilck A., Genomics 50:129-146(1998).Nagase T., DNA Res. 4:141-150(1997).W.S., Sherwood J.K., Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.

Aliases: Cadherin associated Src substrate antibody, Cadherin-associated Src substrate antibody, CAS antibody, Catenin (cadherin associated protein) delta 1 antibody, Catenin delta 1 antibody, Catenin delta antibody, Catenin delta-1 antibody, CTND1_HUMAN antibody, CTNND 1 antibody, CTNND antibody, CTNND1 antibody, delta 1 Catenin antibody, KIAA0384 antibody, p120 antibody, P120 CAS antibody, p120 catenin antibody, P120 CTN antibody, p120(cas) antibody, p120(ctn) antibody, P120CAS antibody, P120CTN antibody

UniProt: O60716

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling