MCM5 anticorps

N° du produit ABIN7181928

L’anticorps Lapin Polyclonal anti-MCM5 a été validé pour WB, IHC, IF et ELISA. Il convient pour détecter MCM5 dans des échantillons de Humain.

Aperçu rapide pour MCM5 anticorps (ABIN7181928)

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Détail du produit anti-MCM5 anticorps

Fonction: MCM5 Antibody

Réactivité croisée: Souris, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from Human MCM5 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MCM5

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Autre désignation: MCM5

Sujet:

Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity By similarity. Interacts with MCMBP.

Robert A. Sclafani, Genetics, May 2002, 161: 47.
Marylynn Snyder, PNAS, Oct 2005, 102: 14539 - 14544.
Christopher J. DaFonseca, PNAS, Mar 2001, 98: 3034.
Cathleen M. Lake, Genetics, Jun 2007, 10.1534

Aliases: CDC 46 antibody, CDC46 antibody, CDC46 homolog antibody, Cell division cycle 46 antibody, DNA replication licensing factor antibody, DNA replication licensing factor MCM 5 antibody, DNA replication licensing factor MCM5 antibody, MCM 5 antibody, MCM5 antibody, MCM5_HUMAN antibody, MGC5315 antibody, Minichromosome maintenance complex component 5 antibody, Minichromosome maintenance deficient (S. cerevisiae) 5 antibody, Minichromosome maintenance deficient 5 antibody, Minichromosome maintenance deficient protein 5 antibody, P1 CDC46 antibody, P1-CDC46 antibody

UniProt: P33992

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA