MARK2 anticorps (pSer595) (Cy3)

N° du produit ABIN714074

L’anticorps Lapin Polyclonal anti-MARK2 a été validé pour WB et IF (p). Il convient pour détecter MARK2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MARK2 anticorps (pSer595) (Cy3) (ABIN714074)

Antigène: MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARK2 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-MARK2 anticorps (Cy3)

Épitope: pSer595

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human MARK2 around the phosphorylation site of Ser595

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MARK2

Antigène: MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

Autre désignation: Mark2

Sujet:

Synonyms: ELKL mot kinase 1, MARK2phospho S595, ELKL mot kinase, EMK-1, EMK1, MAP/microtubule affinity regulating kinase 2, MAP/microtubule affinity-regulating kinase 2, Mark2, MARK2_HUMAN, PAR1 homolog, Serine/threonine protein kinase MARK2, Serine/threonine-protein kinase MARK2.

Background: MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule.stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be coexpressed in a number of selected cell lines and tissue samples. Human MARK2 was shown to be encoded by a single mRNA ubiquitously expressed. This transcription variant includes the alternative exon in the coding region and therefore codes for a longer protein. Multiple splice variants exist for this protein.

ID gène: 2011

UniProt: Q7KZI7

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2