MBTPS2 anticorps
Aperçu rapide pour MBTPS2 anticorps (ABIN7183789)
Antigène
Voir toutes MBTPS2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- MBTPS2 Antibody
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Réactivité croisée
- Souris
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from internal of Human MBTPS2.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))
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Autre désignation
- MBTPS2
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Sujet
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Background: Intramembrane proteolysis of sterol-regulatory element-binding proteins (SREBPs) within the first transmembrane segment thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Site-2 cleavage comes after site-1 cleavage which takes place in the lumenal loop.
Rawson R.B., Mol. Cell 1:47-57(1997).
Ye J., Proc. Natl. Acad. Sci. U.S.A. 97:5123-5128(2000).
Aliases: BRESEK antibody, Endopeptidase S2P antibody, IFAP antibody, KFSDX antibody, MBTP2_HUMAN antibody, MBTPS2 antibody, Membrane bound transcription factor site 2 protease antibody, membrane-bound transcription factor peptidase, site 2 antibody, membrane-bound transcription factor protease, site 2 antibody, Membrane-bound transcription factor site-2 protease antibody, S2P antibody, S2P endopeptidase antibody, Site 2 protease antibody, SREBPs intramembrane protease antibody, Sterol regulatory element-binding proteins intramembrane protease antibody
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UniProt
- O43462
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Pathways
- ER-Nucleus Signaling
Antigène
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