MBTPS2 anticorps (N-Term)

N° du produit ABIN953342

Détail du produit anti-MBTPS2 anticorps

Antigène: MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))

Épitope: AA 14-44, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBTPS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human MBTPS2 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human MBTPS2

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MBTPS2

Antigène: MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))

Autre désignation: MBTPS2 (MBTPS2 Produits)

Synonymes: anticorps BRESEK, anticorps IFAP, anticorps KFSDX, anticorps S2P, anticorps 9630032G22Rik, anticorps AI662535, anticorps LRRGT00063, anticorps membrane bound transcription factor peptidase, site 2, anticorps membrane-bound transcription factor peptidase, site 2, anticorps MBTPS2, anticorps Mbtps2

Sujet: This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome), IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.Synonyms: Membrane-bound transcription factor site-2 protease, S2P, S2P endopeptidas, Site-2 protease, Sterol regulatory element-binding proteins intramembrane protease

Poids moléculaire: 57444 Da

ID gène: 51360

NCBI Accession: NP_056968

Pathways: ER-Nucleus Signaling