NCKAP1 anticorps

N° du produit ABIN7191586

Détail du produit anti-NCKAP1 anticorps

Antigène: NCKAP1 (NCK Associated Protein 1 (NCKAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCKAP1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris, Rat

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human NCKAP1

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:1000-1:2000, IHC:1:25-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NCKAP1

Antigène: NCKAP1 (NCK Associated Protein 1 (NCKAP1))

Autre désignation: NCKAP1 (NCKAP1 Produits)

Synonymes: anticorps HEM2, anticorps NAP1, anticorps NAP125, anticorps p125Nap1, anticorps C79304, anticorps H19, anticorps Hem-2, anticorps Hem2, anticorps Nap1, anticorps mKIAA0587, anticorps mh19, anticorps NCK associated protein 1, anticorps NCK-associated protein 1, anticorps NCK-associated protein 1 L homeolog, anticorps NCKAP1, anticorps Nckap1, anticorps nckap1.L

Sujet:

Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.

Aliases: FLJ11291 antibody, KIAA0587 antibody, Membrane associated protein HEM2 antibody, Membrane-associated protein HEM-2 antibody, MGC8981 antibody, NAP 1 antibody, NAP1 antibody, NAP125 antibody, NCK associated protein 1 antibody, NCK associated protein antibody, Nck-associated protein 1 antibody, Nckap1 antibody, NCKP1_HUMAN antibody, OTTHUMP00000163460 antibody, OTTHUMP00000163461 antibody, p125Nap1 antibody

UniProt: Q9Y2A7

Pathways: Signalisation RTK, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis