Caspase 2 anticorps (AA 251-350) (HRP)

N° du produit ABIN714980

L’anticorps Lapin Polyclonal anti-Caspase 2 a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter Caspase 2 dans des échantillons de Humain.

Aperçu rapide pour Caspase 2 anticorps (AA 251-350) (HRP) (ABIN714980)

Antigène: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 2 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Caspase 2 anticorps (HRP)

Épitope: AA 251-350

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Caspase 2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Caspase 2

Antigène: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Autre désignation: Caspase 2

Sujet:

Synonyms: Apoptosis related cysteine peptidase, CASP 2, Casp 2L Pro, CASP2, Caspase 2 apoptosis related cysteine protease, Caspase2, Developmentally down regulated 2, ICH 1, ICH 1 protease, ICH 1L, ICH 1L/1S, ICH1, ICH1 protease, ICH1L, ICH1L/1S, NEDD 2, NEDD2, NEDD2 apoptosis regulatory gene, Neural precursor cell expressed, Neural precursor cell expressed developmentally down regulated 2.

Background: Caspase 2 has a positive and a negative role in the regulation of the apoptotic process. Overexpression of the full length Caspase 2 (Nedd2/Ich1) mRNA in some cell types results in apoptosis, whereas overexpression of an alternative Caspase 2 splice variant suppresses apoptosis induced by serum withdrawal. Caspase 2 may be activated in vitro by Caspase 1, Caspase 3 and the neutral serine protease granzyme B which is stored in the specialized lytic granules of cytotoxic lymphocytes.

ID gène: 835

Pathways: Apoptose, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway