FGFR4 anticorps (AA 22-369)

N° du produit ABIN7193467

Cet anticorps Souris Monoclonal détecte spécifiquement FGFR4 dans WB, ELISA et FACS. Il présente une réactivité envers Humain et Singe.

Aperçu rapide pour FGFR4 anticorps (AA 22-369) (ABIN7193467)

Antigène: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FGFR4 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 8A1G2

Détail du produit anti-FGFR4 anticorps

Épitope: AA 22-369

Fonction: CD334 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD334 (AA: 22-369) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur FGFR4

Antigène: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Autre désignation: CD334

Sujet:

The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]

Poids moléculaire: 88 kDa

ID gène: 2264

UniProt: P22455

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding