S100B anticorps (AA 1-92)

N° du produit ABIN7193506

Cet anticorps Souris Monoclonal détecte spécifiquement S100B dans WB, FACS et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour S100B anticorps (AA 1-92) (ABIN7193506)

Antigène: S100B (S100 Calcium Binding Protein B (S100B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp S100B est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Clone: 4C7H12

Détail du produit anti-S100B anticorps

Épitope: AA 1-92

Purification: purified

Immunogène: Purified recombinant fragment of human S100B (AA: 1-92) expressed in E. coli.

Isotype: IgG1

Information d'application

Indications d'application: WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur S100B

Antigène: S100B (S100 Calcium Binding Protein B (S100B))

Autre désignation: S100B

Sujet:

Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Aliases: NEF, S100, S100-B, S100beta

Poids moléculaire: 10.7 kDa

ID gène: 6285

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins