MR1 anticorps

N° du produit ABIN7193762

L’anticorps anti-MR1 Monoclonal Souris est utilisé pour la détection de MR1 dans des échantillons de Humain. Il a été validé pour ELISA, IHC, FACS et ICC.

Aperçu rapide pour MR1 anticorps (ABIN7193762)

Antigène: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MR1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 6A5B2

Détail du produit anti-MR1 anticorps

Fonction: MR1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human MR1 (AA: extra(23-302)) expressed in E. Coli.

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur MR1

Antigène: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Autre désignation: MR1

Sujet:

MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.

Poids moléculaire: 39.4 kDa

UniProt: Q95460

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints