Melanoma gp100 anticorps (AA 25-192)

N° du produit ABIN7193921

L’anticorps Souris Monoclonal anti-Melanoma gp100 a été validé pour FACS et ELISA. Il convient pour détecter Melanoma gp100 dans des échantillons de Humain.

Aperçu rapide pour Melanoma gp100 anticorps (AA 25-192) (ABIN7193921)

Antigène: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Melanoma gp100 est non-conjugé

Application: Flow Cytometry (FACS), ELISA

Clone: 5C6G8

Détail du produit anti-Melanoma gp100 anticorps

Épitope: AA 25-192

Fonction: PMEL Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PMEL (AA: 25-192) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Melanoma gp100

Antigène: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Autre désignation: PMEL

Sujet:

This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.

Poids moléculaire: 70.2 kDa

UniProt: P40967