HLA-F anticorps (AA 22-305)

N° du produit ABIN7193964

Cet anticorps anti-HLA-F est un anticorps Souris Monoclonal détectant HLA-F dans WB, ELISA et FACS. Adapté pour Humain et Souris.

Aperçu rapide pour HLA-F anticorps (AA 22-305) (ABIN7193964)

Antigène: HLA-F (HLAF) (HLA Class I alpha F (HLAF))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-F est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 3F11F4

Détail du produit anti-HLA-F anticorps

Épitope: AA 22-305

Fonction: HLA-F Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human HLA-F (AA: 22-305) expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur HLA-F

Antigène: HLA-F (HLAF) (HLA Class I alpha F (HLAF))

Autre désignation: HLA-F

Sujet:

This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.

Poids moléculaire: 39 kDa

ID gène: 3134

UniProt: P30511

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response