ABI1 anticorps (Internal Region)

N° du produit ABIN7213436

Cet anticorps Lapin Polyclonal détecte spécifiquement ABI1 dans WB et ELISA. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour ABI1 anticorps (Internal Region) (ABIN7213436)

Antigène: ABI1 (Abl-Interactor 1 (ABI1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABI1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ABI1 anticorps

Épitope: Internal Region

Fonction: Abi-1 Polyclonal Antibody

Specificité: Abi-1 Polyclonal Antibody detects endogenous levels of Abi-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human Abi-1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur ABI1

Antigène: ABI1 (Abl-Interactor 1 (ABI1))

Autre désignation: Abi-1

Sujet: Rabbit Anti-Abi-1 Polyclonal Antibody,ABI1, SSH3BP1, Abl interactor 1, Abelson interactor 1, Abi-1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Eps8-binding protein, Nap1-binding protein, Nap1BP, Spectrin SH3 domain-binding protein 1, e3B1,ABI1 encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein (abl interactor 1) plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t (10,11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14.,Abl interactor 1

ID gène: 10006

UniProt: Q8IZP0

Pathways: Signalisation RTK, Response to Water Deprivation, ER-Nucleus Signaling