Adenosine A2a Receptor anticorps (AA 90-170)

N° du produit ABIN7219594

L’anticorps Lapin Polyclonal anti-Adenosine A2a Receptor a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter Adenosine A2a Receptor dans des échantillons de Humain.

Aperçu rapide pour Adenosine A2a Receptor anticorps (AA 90-170) (ABIN7219594)

Antigène: Adenosine A2a Receptor (ADORA2A)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adenosine A2a Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Adenosine A2a Receptor anticorps

Épitope: AA 90-170

Fonction: Adenosine A2A-R Polyclonal Antibody

Specificité: Adenosine A2A-R Polyclonal Antibody detects endogenous levels of Adenosine A2A-R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human Adenosine A2A-R at AA range: 90-170

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Adenosine A2a Receptor

Antigène: Adenosine A2a Receptor (ADORA2A)

Autre désignation: Adenosine A2A-R

Sujet: Rabbit Anti-Adenosine A2A-R Polyclonal Antibody,ADORA2A, ADORA2, Adenosine receptor A2a,ADORA2A encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. Adenosine A2a receptor, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.,Adenosine receptor A2a

ID gène: 135

UniProt: P29274

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour, Cancer Immune Checkpoints