ADRA2A anticorps (AA 250-330)

N° du produit ABIN7219826

Cet anticorps Lapin Polyclonal détecte spécifiquement ADRA2A dans WB, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour ADRA2A anticorps (AA 250-330) (ABIN7219826)

Antigène: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA2A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-ADRA2A anticorps

Épitope: AA 250-330

Fonction: Rabbit Anti-AR-α2A Polyclonal Antibody

Specificité: AR-α2A Polyclonal Antibody detects endogenous levels of AR-α2A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human AR-alpha2A at AA range: 250-330

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ADRA2A

Antigène: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Autre désignation: AR-alpha2A

Sujet: ADRA2A, ADRA2R, ADRAR, Alpha-2A adrenergic receptor, Alpha-2 adrenergic receptor subtype C10, Alpha-2A adrenoreceptor, Alpha-2A adrenoceptor, Alpha-2AARAlpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons, the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. ADRA2A encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences.

Poids moléculaire: 50kD

ID gène: 150

UniProt: P08913

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity