ATG5 anticorps

N° du produit ABIN7201349

Cet anticorps Souris Monoclonal détecte spécifiquement ATG5 dans WB, ELISA et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour ATG5 anticorps (ABIN7201349)

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ATG5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 3C7

Détail du produit anti-ATG5 anticorps

Fonction: Mouse Anti-ATG5 Mouse Monoclonal Antibody (3C7)

Specificité: The antibody detects endogenous ATG5 protein.

Purification: Protein G

Immunogène: Recombinant Protein of ATG5

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IF 1:100-500,ELISA 1:1000-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ATG5

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Autre désignation: ATG5

Sujet: Autophagy protein 5, APG5-like, Apoptosis-specific proteinATG5, also named as APG5L and ASP, belongs to the ATG5 family. It is required for autophagy. It plays an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. It mediates autophagosome-independent host protection.

Poids moléculaire: 55kD

ID gène: 9494

UniProt: Q9H1Y0

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy