L’anticorps anti-ATG10 Polyclonal Lapin est utilisé pour la détection de ATG10 dans des échantillons de Humain et Souris. Il a été validé pour ELISA, IHC et IF.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Date de péremption
12 months
Antigène
ATG10
(Autophagy Related 10 (ATG10))
Autre désignation
ATG10
Sujet
Ubiquitin-like-conjugating enzyme ATG10, Autophagy-related protein 10, APG10-likeAutophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: aTG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A, MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al. 2003 ATG10 (Autophagy Related 10) is a Protein Coding gene. Diseases associated with ATG10 include Anthracosis. Among its related pathways are Cellular Senescence (REACTOME) and Autophagy Pathway.