BACE2 anticorps (AA 210-290)

N° du produit ABIN7227452

L’anticorps anti-BACE2 Polyclonal Lapin est utilisé pour la détection de BACE2 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour BACE2 anticorps (AA 210-290) (ABIN7227452)

Antigène: BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BACE2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-BACE2 anticorps

Épitope: AA 210-290

Fonction: Rabbit Anti-BACE2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of BACE2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human BACE2 protein at AA range: 210-290

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur BACE2

Antigène: BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

Autre désignation: BACE2

Sujet: Beta-secretase 2, Aspartic-like protease 56 kDa, Aspartyl protease 1, ASP1, Beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, Down region aspartic protease, DRAP, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretaseBACE2 encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 56kD

ID gène: 25825

UniProt: Q9Y5Z0