Betacellulin anticorps (Internal Region)

N° du produit ABIN7218780

Cet anticorps Lapin Polyclonal détecte spécifiquement Betacellulin dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Betacellulin anticorps (Internal Region) (ABIN7218780)

Antigène: Betacellulin (BTC)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Betacellulin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Betacellulin anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-Probetacellulin Polyclonal Antibody

Specificité: Probetacellulin Polyclonal Antibody detects endogenous levels of Probetacellulin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human Probetacellulin

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Betacellulin

Antigène: Betacellulin (BTC)

Autre désignation: Probetacellulin

Sujet: BTC, ProbetacellulinBTC encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.

Poids moléculaire: 20kD

ID gène: 685

UniProt: P35070

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway